Modafinil and Caffeine
I’ve tried time and time again to use my modafinil as an as-needed supplement, but I find myself needing a pick-me-up more than once a week.
As much as I love caffeine, the effects are too short-lived to be effective for 16+ hours of productivity, so I turn to modafinil for a longer, cleaner feeling of wakefulness.
Plus, like everyone, I build a tolerance to caffeine pretty quickly. This means I need to take more and more caffeine to get the same effects as I did in early use stages. Since I use it for my pre workout supplement, I don’t want to rely on it to wake me up as well. This would just dilute its effectiveness. Thus, I turn to modafinil (to which I had no tolerance); however, it comes with similar drawbacks as well.
As many of you already know, modafinil and caffeine (as well as everything else) has a tolerance effect in the body, and I’ve almost reached a point of ineffectiveness. This happened to me once over the summer as well (I got to the point of taking modafinil every day) and it was an unfortunate waste of money.
Using Yohimbine to Counteract Modafinil Tolerance
I recently heard of a potential synergy between modafinil and yohimbine. I hadn’t done much research on yohimbine in the past, but it’s primarily marketed as a weight-loss supplement with stimulatory effects. I came across an article that mentioned that modafinil-induced wakefulness and focus was significantly increased with a small dose of yohimbine.
What are Yohimbine and Modafinil?
Here is a brief background of both supplements for those who are unfamiliar with them:
Modafinil is a drug that requires a prescription in the United States and is used to promote wakefulness. It is primarily used by individuals with narcolepsy or sleep apnea, but is also used for attention disorders, mood disorders, fatigue, and as a nootropic for cognitive enhancing purposes.
Yohimbine is available for purchase online and in many brick and mortar stores. It is primarily used for fat loss; however, it also has stimulant and aphrodisiac properties. As it is highly versatile, yohimbine is a very popular supplement among men and women. However, as I said before, I was interested in its potential synergy with modafinil.
Powder City was nice enough to send me a sample of yohimbine, and I was amazed with what I found.
It’s generally advised that these drugs should not mix (because yohimbine has inhibitor properties making modafinil slightly more toxic), but in low doses of each, this wasn’t a concern of mine.
I had made it through the entire week without the assistance of any supplements, but Friday came around and the entire week suddenly caught up with me. I finished class and had an hour or so before going to work, but sitting in my chair, I was having an insanely difficult time keeping my eyes open.
I didn’t want to take anything with caffeine in it, because I like to save my caffeine ingestion for the gym. I was about to take a quick powernap, but remembered that I had some yohimbine and modafinil on my shelf.
I cut the modafinil tablet in half (100mg), and took one capsule of yohimbine (2.5mg). Alone, these would not have done much for me, but together, I was awake and ready to go within half an hour.
After a shift at work, I went to the gym with one of my buddies who practices MMA (Mixed Martial Art) fighting all over the country, and with the help of a little caffeine powder, I was able to power through a 2-hour workout.
Individuals considering this combination should proceed with caution; yohimbine is highly stimulatory in some, but for me, it was just what I needed.
The Adrafinil Stack
Adrafinil is equally as effective as modafinil. This is because adrafinil is a prodrug of modafinil meaning it metabolizes into modafinil within the body. As a result, you reap the same benefits. Plus, you can stack adrafinil with other supplements as well. Also, unlike modafinil, you do not have to have a prescription to buy adrafinil.