Alpha GPC Dosage and Benefits

Proper Alpha GPC dosage is part of the nootropics puzzleAlpha GPC powder is one of the newcomers to the field of mind boosting supplements. It is certainly something which bears consideration since there are claims that it acts as a cognitive enhancer.  There has been some promising research already and the potential of Alpha GPC may be to help anyone suffering from some type of cognitive decline.

What is L-Alphaglycerylphosphorylcholine (Alpha GPC)?

Alpha GPC is a phospholipid metabolite that is found concentrated in neuronal membranes. This supplement is able to deliver choline to the brain. The actual supplement itself is made from lecithin and is a nutrient derived from other soy phospholipids as well. The substance itself is well-absorbed and capable of crossing the blood-brain barrier. Once in the brain it helps to support a number of learning processes and general functioning.

Alpha GPC Benefits

The main benefits of this supplement seem to be primarily related to mental functioning and cognition. This includes increased memory, focus and concentration, and even neuron protection. It helps to directly increase the synthesis and secretion of acetylcholine and improves signal transmission throughout the brain.

It is also believed that this supplement helps to increase the secretion of human growth hormone (HGH). This should be a huge benefit to body builders and other weight training athletes since increased circulating HGH should enhance the ability to build muscle, engage in more intense training, and improve recovery ability from such training sessions.

Liver function and protection is another benefit of Alpha GPC. This supplement raises the lipotrophic functions of the liver through the increased release of choline. It also helps to protect against a fatty liver and the resulting diseases such as obesity and diabetes. It may even help to protect against damage done by heavy alcohol consumption.

Alpha GPC Side Effects

Anyone who might be interested in having their mental abilities increased naturally and without any side effects should definitely consider this supplement.

Alpha GPC Dosage

A recommended alpha GPC dosage has not yet been established for Alpha GPC. Many experts suggest taking around 300 mg per day. This can be in a single dose or divided administrations. In order to guard against tolerance it is also recommended to limit yourself to three or four days per week. You can buy Alpha GPC in bulk and control your own dose.

Centrophenoxine and Piracetam Combo and Dosage

Centrophenoxine

Centrophenoxine is a nootropic known as a cognitive enhancer and anti aging supplement. It can increase energy as well as improve longevity of brain health by refreshing the cells in the body and brain. It is also known as an anti aging supplement because of its ability to help age related learning difficulty, clear age and live spots on the skin, and help with age related learning difficulty. The anti aging system of centrophenoxine works by clearing the lipofuscin deposits that accumulate in the cells and body. Lipofuscin deposits are often the result of dark spots on the skin of older people that you may have noticed before.

Centrophenoxine Benefits

Cellular damage and age related brain damage can be slowed by centrophenoxine which clears the deposit of potassium in cells which is what lipofuscin is. This deposit buildup stops the cells from functioning as they normally would by blocking the cells source of oxygen and nutrition. As a result the cells die because of the absence of blood and oxygen and this causes accelerated aging, memory loss, difficulty learning and appearance of brown spots on the skin. Centrophenoxine also increases the glucose uptake of the cells. This protects brain cells. Centrophenoxine powder is often used in a combination with piracetam to help deal with and reduce the effects of age-related memory loss. Centrophenoxine combined with piracetam has been clinically proven to be effective for promoting and preserving brain health.

Centrophenoxine Dosage

Centrophenoxine dosage is generally 1-3 doses of 250mg per day for younger individuals who are seeking neurological enhancement and neuronal protection. For older adults the recommended dosage is 3-6 doses of 250mg

Piracetam

Piracetam is also a cognitive enhancer that has been observed to increase energy and improve memory in healthy young adults and the elderly. It was found to be potentially devoid of any toxicity and beneficial for people who suffered from memory loss, memory decline, lack of concentration, and is generally effective in people suffering from age-related memory loss. In addition to improving memory, enhancing cognition and increasing concentration, piracetam has also been found useful for clotting and coagulation. Sometimes piracetam is used as an anti depressant since it increases glucose uptake of the brain cells and stimulates chemicals in the brain such as serotonin and dopamine.

Piracetam Benefits

So piracetam is reported to be very effective for cognitive impairment which works through various mechanisms some of which enhance membrane fluidity by interacting directly with cell membranes. Centrophenoxine combined with piracetam can work both as a cognitive enhancer and anti aging supplement.

Piracetam Dosage

Normal piracetam dosage is usually around 1200mg to 4800mg per day for adults, so make sure to stay within the recommended ranges of both supplements.

Piracetam and Centrophenoxine Combo

This combination has been reported to be very effective although research on piracetam notes that it is much more effective as a preserver although it is also a cognitive enhancer. So combining it with centrophenoxine makes it that much more powerful of a combination because now you get both preservative properties and memory enhancing properties.

Sources:

  1. http://www.ncbi.nlm.nih.gov/pubmed/16284628
  2. http://www.ncbi.nlm.nih.gov/pubmed/8367013
  3. http://www.ncbi.nlm.nih.gov/pubmed/1098982

Benefits of Sulbutiamine and Caffeine Nootropic Combo

Sulbutiamine and caffeine is a fairly new nootropic combination but seems promising. Sulbutiamine is a nootropic that is designed to improve your mood, boost your memory and give you an increase in energy. What makes this combination unique is that sulbutiamine has energy boosting properties similar to that of caffeine, but of course it is taken with caffeine which can give you even more energy and possibly reduce the effects of a caffeine crash. Sulbutiamine raises the levels of thiamine and thiamine phosphate esters in the brain, which results in increased focus and endurance.

Sulbutiamine Benefits

Scientific studies have also been done to learn more about sulbutiamine benefits. Research has shown that sulbutiamine effects people who suffer from asthenia, which is a medical condition where people experience severe fatigue and muscle weakness. This is because sulbutiamine helps aid in boosting energy and athletic performance. Sulbutiamine is also often added to energy drinks and studies have been done that shows significant increases in mental focus and reaction time performance. The sulbutiamine dosage that is recommended is between 200mg and 500mg up to two times daily with food. Anyone taking sulbutiamine powder or capsules should never exceed that amount within a 24 hour time period.

Another study done for mice was said to have improved memory by increasing retention, which resulted in increased performance. It has also been tested on patients with chronic post infectious fatigue (CPIF) with doses of 400mg daily, which noted that the group had significantly less fatigue than the group with the placebo. Improvement was reportedly noted in 91.37% of the people tested with multiple sclerosis, with 74.13% of them reporting that the improvement was substantial. In addition to improved mental focus and increased fatigue, there are also reported effects on the eyes and sexual performance.

Thiamine is known to be lower in glaucoma patients, with studies that show that thiamine injections increase visual acuity, and sulbutiamine is a molecule in which two thiamin (B1) molecules are bound together. The study showed that sulbutiamine was able to reduce cell death when cells were deprived of serum. Sulbutiamine benefits for psychogenic erectile dysfunction have also been noted, which was said to have increased performance. Sulbutiamine seems to have a lot of benefits and positive effects, so what happens when sulbutiamine is tied in with the benefits of caffeine in a nootropic combo?

Caffeine Benefits

Caffeine is also highly stimulatory and improves physical performance when it comes to both endurance and strength. It is also classified as a nootropic due to its mentally stimulatory actions and sensitization of neurons. When caffeine supplements are combined with sulbtiamine powder or capsules, the affects become apparent. It is reported that this nootropic combo will give you a high boost in energy, with significant increases in endurance. It has been reported that the crash that comes as caffeine wears off is greatly reduced, which is more than likely due to the sulbutiamine supplement that is added. This nootropic stack is highly effective and a great choice if you want to see improved mental performance and increased physical endurance.

Sources:

  1. http://www.ncbi.nlm.nih.gov/pubmed/4059305
  2. http://www.ncbi.nlm.nih.gov/pubmed/15951087
  3. http://www.ncbi.nlm.nih.gov/pubmed/10573727

Best Nootropics for Memory in the Short Term

Best nootropics for memory, huperzine-a.When we start to become very interested and specific in our health and fitness related goals we see a direct correlation in the increase of supplements and our knowledge of the field. Specifically we begin to discover certain methods of reaching a level that we never thought to be attainable before and in most cases is not attainable naturally. If you match this profile then you may have already stumbled upon the family of nootropics. Often referred to as memory or cognitive enhancers, nootropics are a class of substances that can be taken via supplements and functional foods. They can enhance and improve quality of life in a rather specific manner. The specific attribute we want to look at in this analysis of nootropics involves short term memory.

Nootropics for Short Term Memory

Short term memory is a very often overlooked yet essential part of our daily lives. In fact, many people struggle with severe impaired short term memory and are not aware of it or its implications. On a personal level I can say that I struggle with short term memory in that I sometimes struggle to remember what I had for breakfast six hours ago, yet I can remember a conversation I had with a significant other over six years ago. Why is this, and what can nootropics do for me to help alleviate this problem?

While you may have heard of prescription strength nootropic solutions, this analysis will focus on over the counter products that act in a similar and in some cases enhanced fashion in contrast to their prescription strength counter parts. Two supplements that have been shown to do just that are huperzine-A and piracetam.

Huperzine A

Huperzine-A is an extracted compound from the herbs of the huperzicae family and is known to be an acetylcholinesterase inhibitor, essentially meaning that it stops an enzyme from breaking down acetylcholine. Still lost? Acetylcholine is known as the learning neurotransmitter and is also involved in muscle contraction; therefore inhibiting the breakdown of this neurotransmitter leads to an increased presence in the brain and increased benefits. Note that this is a very simplified breakdown of a complicated process in the brain and in no means should serve as scientific reference.

Piracetam

The next nootropic that has been strongly linked to short term memory improvement is none other than the father of nootropics, piracetam. Piracetam is a member of the racetam family and is among the most researched nootropics. In research specific to memory loss piracetam has shown a significant ability to increase the power of memory in healthy human after only a two week period. This comes in addition to the many other health benefits that are often associated with piracetam and its family of nootropics. With little to no side effects reported and a very low toxicity piracetam makes a great candidate for improving short term memory loss in addition to being a solid choice for an everyday cognitive enhancing supplement.

How to Take Nootropics for Memory

With all supplements and nootropics are certainly no exception it is important to pay attention your body’s individual response. Additionally one should always carefully read the packaging and label information on any new product before implementing it into your daily stack or routine.

Sources

  1. www.ncbi.nlm.nih.gov/pubmed/826948
  2. http://pubs.acs.org/doi/abs/10.1021/ar9800892

 

Best Nootropics for Anxiety

Anxiety is an important part of human physiology and in many ways is what keeps us from living an accident prone disastrous lifestyle. A natural way of our body telling us we are in a potentially dangerous or harmful situation anxiety is a necessary response that promotes longevity in human life. With all that said; anxiety is often associated with stress and is generally seen in a negative light in most circles. The true villain here is “over-anxiety” and the body’s physical response which can include an increase in perspiration and heartbeat.  If we were anxiety free all the time we would be much more likely to engage in dangerous and potentially life threatening activities that would greatly hamper our life expectancy. So, why am I telling you all of this and how can we use nootropics to curb intense anxiety that may constrain our lives?

Nootropics are often used to enhance memory and improve cognitive function but they have also been shown to have anti-anxiety and stress reducing properties. Specifically there are certain nootropics that when taking in conjunction work synergistically to achieve this desired effect. There are a number of nootropics available that can alleviate anxiety and in many cases a trial and error method of experimentation may be required to find the optimal solution for your needs.

Nootropics for Anxiety

In this analysis of anti-anxiety nootropics we will take a look at a few different nootropic options including theanine, GABA, 5-htp, bacopa, and rhodiola. Theanine is the only nootropic that has the ability to simultaneously increase serotonin and GABA levels, both of which are associated with lowering anxiety levels. Alternatively direct GABA supplementation is more effective in raising GABA levels and 5-htp or bacopa can be more effective in raising serotonin levels. So, if you are looking for a one and done solution theanine seems to be your best option. Rhodiola is one of the only nootropics that specifically halts the breakdown of serotonin in the brain and has shown a significant effectiveness in research, therefore I suggest supplementing with rhodiola in addition to other nootropics in most cases. A combination of rhodiola and either 5-htp (a naturally occurring anti-anxiety and stress reducing amino acid) or bacopa (an herb that has shown to increase serotonin in the brain) is recommended for the best anti-anxiety results with nootropics.

While this recommended combination/stack has shown to be effective and is a good starting point, the topic of nootropics is notorious for being uncharted territory and should be approached with that in mind. This means that one should always pay attention to your body’s individual response and conduct personal research on a supplement or supplements before consuming them.

Nootropic supplementation can be an exciting and often very effective method of attaining your desired results in your personal health related goals. Always pay attention to your products packaging and label information for dosing guidelines and it is recommended you consult a doctor before implementing nootropics in to your daily routine.

Sources

http://www.ncbi.nlm.nih.gov/pubmed/12467378

http://www.ncbi.nlm.nih.gov/pubmed/11498727

New to Nootropics? Information to Get You Started

Nootropics are well known memory enhancers. Coined in 1972, the term is still relatively fresh in the supplement world and in many ways could be classified as uncharted territory. Nootropics are supplements, nutraceuticals, or functional foods that improve intelligence, memory, cognition, motivation, and attention. There are an overwhelming amount of nootropics available on the market today and it can be a difficult task to find the optimal mix or stand-alone nootropic for you. If you want to either try nootropics for the first time and don’t know where to get started or are more experienced but want an option that is backed by good research then I suggest the nootropic piracetam.

Piracetam is a member of the racetam family, a group of cognitive enhancers with a common base structure. It has been labeled the father of nootropics as it was the first substance to receive the label and continues to be the leading choice for many people experimenting with different options. So, why should you choose piracetam over other nootropic supplements and how should we implement nootropics in general into our daily routine?

The leading argument in piracetam’s favor is similar to many arguments that surround various nootropics in that it touts the ability to enhance memory and improve cognitive function in both healthy and unhealthy adults. Research has shown significant memory enhancing effects after a consistent dosing of piracetam; specifically verbal learning was shown to have significantly increased after only two weeks. In addition to memory enhancement, piracetam has shown the ability to provide the user with an improved cognitive function in day to day activity. A meta-analysis that looked at 19 different double-blind placebo controlled studies concluded that piracetam does have a significant benefit in regards to cognitive function.

The many benefits associated with piracetam include but are not limited to: cardiovascular system protection, metabolism boosting ability, improved blood circulation, hearing improvement, detoxifying agent, and the ability to counteract hypoxia, short term memory loss .

Piracetam, a cyclic derivative of GABA is available as an over the counter supplement. I urge you to do your own research on nootropics before adding them to your daily routine or stack. While piracetam has shown no adverse side effects and a very low toxicity there are still unknown variables that one must consider as nootropics in general are a fairly new and under studied family of supplements. With that in mind make sure to pay attention to your body’s individual response and the product’s label information to be as safe as possible while using nootropics.

Sources

  1. http://www.ncbi.nlm.nih.gov/pubmed/826948
  2. http://www.ncbi.nlm.nih.gov/pubmed/12006732

The Best Nootropic for Memory in the Long Term

Nootropics are highly popular among people who want to increase their brain capacity and improve their memory. However, many of the nootropics available only work on the short term but not a lot of people are willing to invest in nootropics that will not benefit their mental health in the long term. It is no secret that memory span will shorten as you get older. Yet for some older people, memory does not seem to be too big of an issue and they can recall things much quicker than their peers. There are various reasons this could happen, but studies have shown that nootropics can both protect the memory from degrading in older subjects, as well as enhance memory.

Vinpocetine is a semisynthetic extract from the periwinkle plant. This nootropic has been reported to help increase cerebral blood flow and enhance concentration and memory. Many studies have been done on this nootropic in Europe and clinical studies found that it provides several advantages to the human brain when taken. It is often used to help with memory loss and other age related mental disorders. The benefits of taking vinpocetine are neuroprotective effects, increased blood flow to the brain, it acts as an anti-inflammatory agent, and it improves long term memory.

Best Nootropic for Memory: Oxiracetam

What is the best nootropic for memory enhancement? Racetams of course are some of the most popular memory enhancing nootropics. Oxiracetam, to be specific, is one of the most potent racetams available. Oxiracetam is another water-soluble nootropic, and is generally recommended to help fight cognitive decline that comes with aging. Its neuroprotective properties help improve the brain’s physical health while also helping with age related issues such as memory loss. This is done by stimulating the production of the neurotransmitters glutamate and acetylcholine. Acetylcholine activates muscles in the peripheral nervous system and is the only neurotransmitter used in the motor division of the somatic nervous system.

The benefits of taking oxiracetam are improved effectiveness of brain training games, increased motivation and focus, increased spatial learning and contextual learning abilities, and improved memory. Oxiracetam has various positive effects as a neuromodulator which means that it affects the brains short term memory, long term memory, and the ability to learn.

Omega-3 For Brain Health

Omega 3 fatty acids are essential for good health. Not only are the vital, the human body cannot make them; we must obtain them from our diet or through supplementation. These substances have been extensively researched and are considered to be important in reducing the risk of heart disease. However, recent studies have also confirmed that these supplements play an essential role in maintaining brain health. These acids appear to be highly concentrated in the brain and may be important for numerous cognitive functions as well.

A Natural Brain Booster?

The majority of your brain consists of fatty acids. In fact, most of these essential fatty acids (EFAs) within the brain are indeed omega 3’s. Since these good fats can only be obtained through diet and supplementation it only makes sense that increased consumption can help restore and maintain proper brain function. Studies have shown that diets rich in omega 3 fats can result in increased learning ability, problem solving skills, focus, memory, and even improved communication between cells. It can even help to promote positive mood and emotional balance, even as we age.

How EFAs Benefit the Brain

In order to communicate properly, the cells within the brain must have flexible membranes so that vital molecules may easily pass through. Unfortunately, with age and an accumulation of saturated fats within the diet, these membranes can become rigid and inflexible, leading to poor communication and all sorts of mental and cognition problems.

Omega 3 supplementation can actually serve to help restore the pliable and flexible cell membranes needed for proper brain functioning. This naturally increases inter-cellular communication and helps to restore the proper balance. Also, omega 3 fatty acids act as a blood cleanser. When the blood is less ‘sticky’ it is also more fluid and better able to flow throughout the body. Since blood is the main transportation method to the brain this allows for increase oxygen uptake, helping to feed the brain.

Additional Brain Benefits

A number of studies have also associated low levels of omega 3’s with cognitive decline. However, many scientists are starting to come to the understanding that these supplements can help to protect the brain against age-related cognitive decline. There are also similar studies suggesting that these supplements may prove helpful for mood and behavioral conditions.

The bottom line here is that these omega-3 fatty acids are good for you. If you are not taking them already then you need to start. It is certainly cheap insurance against age-related cognitive decline or something even worse.

Arginine for Immune System Health

Sometimes life seemingly gives us more responsibilities than we can handle. Our days are filled with heavy workloads, home repairs, and possibly even a new child. But, if our personal health deteriorates and ultimately becomes a difficult struggle, we find ourselves ill prepared to tackle these tasks. Falling ill can lead to sick days from work and, subsequently, less funds to finance projects, repairs, or the ability to go out to dinner every now and then. Accomplishing any of our goals is directly dependent on our bodies staying healthy and properly fighting off illnesses. As we grow older, our immune system weakens and we are much more susceptible to deteriorating health, both physically and cognitively. With a supplement of Arginine, our immune system can give us a boost to help fight off infection and repair tissue damage so that we can place a better focus on the things we find most important.

What is Arginine?

Arginine [1, 2] is an amino acid which becomes essential during times of extreme sickness or serious health concerns. Although Arginine is found naturally in the body, continued stress on the body or exposure to illness can weaken our immune functions, thus, Arginine becomes essential in fortify our body’s defenses. Being a known vasodilator [2], Arginine also helps to increase blood flow throughout the body which can decrease blood pressure and the possible overexertion of the heart and other organs.

How can Arginine Benefit You?

When we become ill or we sustain an injury from intensive exercise, our body immediately begins to repair damage. But, during an extended recovery, both the body and the immune system occasionally need something to enhance and energize its reparative functions. Two different studies have indicated that supplementation during recovery decreased wound healing time, increased protein count, T-cell function, and thymic immune function. Arginine ultimately decreased wound duration as well as overall recovery time. While many individuals can benefit from this supplement, Arginine has proved especially effective in patients 65 years or older. Age often brings a decrease in immune function and along with it, an increased susceptibility to illness and serious injury.

In relation to supplementation to lessen recovery time after intensive weight training or exercise routines, Arginine also acts as a precursor to the amino acid Glutamine [2]. Also conditionally essential to the body during instances of increased bodily stress, Glutamine works as the preferred and essential fuel for the body’s immune system instead of glucose. Additionally, Arginine’s vasodilatory [2] action increases oxygen delivery as well as muscle function during exceptionally difficult training sessions. Arginine not only helps younger bodies perform at their best, but it also aids aging bodies in the fight against life’s many challenges.

Sources:

  1. http://en.wikipedia.org/wiki/Arginine
  2. http://examine.com/supplements/Arginine/