Using Nootropics for Motivation

Nootropic supplements are finding more and more uses in the area of brain enhancement. The term nootropic was originally coined in 1972 by Dr. Corneliu E. Giurgea and is derived from the Greek word “mind” and “to turn”- a fitting description of the alteration that these supplements can accomplish in the brain.

Nootropics can enhance memory, motivation, cognition, attention, alertness and more. Although the effect of each nootropics can help boost motivationsupplement will vary from person to person, there is always a common denominator.
The majority of the nootropics produce some form of motivation but let’s take a look at a few that have been especially noted to increase motivation:

Sulbutiamine

Sulbutiamine is a derivative of Vitamin B1. Because of its ability to cross the blood barrier faster than Vitamin B1, this supplement is stronger in terms of effects. Like thiamine, sulbutiamine works by aiding in the biosynthesis of acetylcholine and GABA but has a faster absorption rate.

Benefits of sulbutiamine include improved memory and stimulation. It has been used by athletes as a legal performance enhancer. Sulbutiamine causes upregulation of the reticular-activating system in the brain, which is the center of arousal and motivation.

Dosage of sulbutiamine is reported to be 12.5mg/kg although this may vary. Side effects include nausea, skin rash, headaches and anxiety. Thankfully there are nootropics for anxiety.

Aniracetam

Aniracetam is one of the most common racetams and is a cognitive enhancer known to enhance memory and concentration. It works by increasing communication between the left and right sides of the brain. This boost increases creativity, perception, and more. This supplement stimulates the function of neuronal receptors by means of glutamic acid which aids in the memorization process.

Aniracetam is usually stacked with choline in order to reduce the side effects that commonly occur with the use of aniracetam. Dosage of aniracetam is 1500mg taken twice a day in 750mg doses.

Vinpocetine

Vinpocetine is a cognitive enhancer that works by increasing the blood circulation in the brain. This increase in turn increases cellular efficiency. Additional benefits of vinpocetine include enhanced alertness and mood enhancement. Standard dosage of vinpocetine is 10mg taken three times a day.

Conclusion

When it comes to the search for nootropics for motivation, there are no hard rules. The fact remains that everyone reacts differently. It is noteworthy that supplements that have been considered to be good motivators, such as caffeine and amphetamines, can in fact have the opposite effect. According to a report, these stimulants do not actually raise motivation levels especially in individuals who are motivated.

With this in mind, one should carefully consider the nootropics taken for motivation—making the wrong choice can have negative effects. The aforementioned nootropics are what have been recommended by many.

Noopept and Megadosing

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Noopept has noticeable nootropic effects due to its high potency. Many people use noopept to improve mood, focus, and motivation.

What is Noopept?

Scientifically known as N-phenylacetyl-L-prolylglycine ethyl ester, this nootropic supplement is patented in the United States and in Russia where it is commonly used. Noopept derives from the racetam family and works in a similar manner as the other racetams but is up to 1000 times more potent than the most common racetam, piracetam.

Noopept is a peptide (a compound consisting of two or more amino acids linked in a chain) that has been shown to be more powerful than Piracetam. Aside from being a brain booster, it is also reported to have anti-inflammatory benefits and antioxidant qualities.

How does it work?

The method of action used by noopept is similar to the group of cognitive enhancers called racetams. Although the exact way that racetams function is yet to be understood, these compounds are said to work by activating the glutamic receptors and inhibiting the hydrolization of acetylcholine in the brain. The breakdown of acetylcholine (the brain’s primary neurotransmitter) is what causes memory loss and other degenerative effects in terms of cognition. Noopept also seems to stimulate an anxiolytic response in animal and human models as well as dopamine receptor and serotonin-receptor sites.

What are the benefits?

Some of the noticeable noopept effects are:

  • Increased overall cognitive performance,
  • Increased learning ability,
  • Enhanced memory,
  • Improved reflexes and perception,
  • Improved mood.

Noopept and Megadosing

The recommended dosage for noopept is 10-40mg a day. Noopept is known to be one of the nootropics that produces noticeable effects after short usage. This rapid action makes it a highly-potent supplement that is recommended to be taken carefully.

A common practice when it comes to supplementing with nootropics is called megadosing. Megadosing is the consumption of an exceptionally large dose of a supplement. In the case of noopept, some users have experimented with megadoses and received good results. Megadosing with up to 100mg of Noopept twice a day improves mood, sensory enhancement, and general cognition.

Before you decide to megadose with noopept, it is important to assess your tolerance at lower dosages.

Can Nootropics Enhance Your Sense of Taste?

Also referred to as memory supplements, neuro enhancers, or cognitive enhancers, nootropics have become the center of attention in the supplement community in the past few years. There are various classifications of nootropics that use different mechanisms of action, one of the most popular being those from the racetam family.

Nootropics have a variety of effects, such as sensory enhancement. Before we go into that, let’s have a brief overview of nootropics can boost the sensesthe most common nootropics and their uses.

Common Nootropics and Their Uses

Piracetam– a derivative of the neurotransmitter gamma-aminobutyric acid (GABA), this nootropic belongs to the racetam family and is usually used as a brain booster. Piracetam also has neuroprotective and anticonvulsant properties and also improves neuroplasticity. Dosage is 2-6 grams per day.
Uses:
• Slows deterioration of the brain
• Improves alertness, socialization and I.Q
• Increases memory and verbal learning

Aniracetam– a fat-soluble racetam (thereby fast acting) memory supplement that impacts IQ and creativity. Aniracetam is also known to have a period of effectiveness between 6-7 hours. It also is said to have stress-relieving properties.
Uses:
• Potentially benefits memory formation
• Improves judgement and mood qualities

Oxiracetam– another member of the racetam family that appears to improve brain function.

Vinpocetine– a nootropic that is known to enhance blood flow to the brain, eyes and ears. Vinpocetine is a derivative from Vincamine.
Uses:
• Stimulates information processing, attention, cortical/behavioral arousal, learning, and memory
• Reduces abnormal blood clots
• Boosts mental energy and blood circulation

L-theanine– an amino acid that is involved in inhibiting stress, anxiety, worry, and nervousness.

Choline– a common supplement among nootropic stacks because of its ability to increase the levels of the neurotransmitter acetylcholine which is usually depleted with the intake of some racetams.

Nootropics and Sensory Enhancement

Now back to the question of whether nootropics can have sensory enhancement abilities especially in the area of taste. The bottom line is that there is no conclusive evidence as to the ability of nootropics to enhance taste in particular. However, nootropics in the racetam family have benefits including increased sensory perception. Users of nootropics report effects such as enhanced vision (colors and objects become more vivid), enhanced hearing, and enhanced touch. Aniracetam is also among the nootropics that users claim to have sensory enhancement benefits. Other nootropics with this effect include Piracetam and Noopept.

Noopept vs Pramiracetam

 

The nootropics noopept and piracetam are two popular cognitive enhancers available on the market today. Both supplements are safe for consumption and are available in many countries.

Pramiracetam is a nootropic derived from piracetam and is considered to be more potent[1]. Noopept is a peptide-derived nootropic that is closely related to the racetam family.

Let’s go into a little detail on both of these supplements.

What is noopept?

This cognitive enhancer is said to be stronger than piracetam and thus much more potent (10-30mg of noopept vs. 2-4g of piracetam). This nootropic is a very popular memory supplement and is categorized as a neuroprotectant[2].

How does noopept work?

Noopept ‘s mechanism of action is similar to the that of the racetam family. This mechanism entails stimulating the acetylcholine system as well as dopamine receptor sites. Acetylcholine is the neurotransmitter responsible for learning, so boosting the amount and duration of exposure is obviously a major plus. Furthermore, noopept also stimulates certain serotonin receptors which contributes to its mood boosting qualities[3].

Benefits of noopept

Noopept comes with many benefits:

• Increase in attention and memory
• Improvement in reflexes and perception
• Enhancement in logical thinking
• Boost in mood

The recommended dosage for noopept is 10-30mg taken daily. Noopept effects vary from person to person and some noticeable side effects include headache, insomnia, and fatigue. Since noopept is extremely potent, dosage should be strictly adhered to.

What is pramiracetam?

Pramiracetam is a nootropic that belongs to the racetam family and has been in use since the early 1980s. It shows potential in cognitive enhancement and is used to help alleviate symptoms of cognitive diseases [4].

Pramiracetam How does it Work?

Like its compatriots in the racetam family, pramiracetam works by increasing the uptake of choline in the brain thereby aiding in the efficient functioning of the acetylcholine system. This efficiency contributes greatly to memory formation and general cognition[5]. Such a mechanism of action has made pramiracetam one of the favorites among the cognitive enhancer supplements.

Pramiracetam Benefits

The most recognized benefits of pramiracetam include:
• Enhancement in mood
• Increase in long and short-term memory
• Increase in blood flow in the brain
Neuroprotective qualities

Pramiracetam Dosage

Pramiracetam is considered one of the strongest racetams; the recommended dosage is 250mg per day[6]. Due to the bitter taste that pramiracetam powder has, many users opt to purchase pramiracetam capsules instead (or flavors can be used to mask the taste as well).

Noopept vs Pramiracetam

Noopept and pramiracetam have also been used together in a nootropic stack and users claim that the emotionally dulling effect of pramiracetam counters the irritability effect of noopept. [7].

Both supplements are among the list of the strongest (produces the most noticeable effect) nootropics. For first-time users, increased mental clarity and enhanced cognition are noticeable[8].

As to the question of noopept vs pramiracetam and which among the two is the better nootropic, there isn’t always a definite answer. It would really depend for what you are aiming. One thing is for sure: these two supplements are among the strongest and should be handled with care.

I personally prefer noopept as it requires a much smaller dosage, so I don’t need to order very much at a time.

Sources

1. http://en.wikipedia.org/wiki/Pramiracetam
2. http://www.ncbi.nlm.nih.gov/pubmed/2011259
3. http://onlinelibrary.wiley.com/doi/10.1002/ddr.430030503/abstract
4. http://www.braintropic.com/racetam-comparison/
5. http://www.longecity.org/forum/topic/60676-pramiracetam-noopept-exam-log/
6. http://www.whatarenootropics.com/what-best-racetam-nootropic/

Centrophenoxine Review

Centrophenoxine is an ester of pCPA and DMAE and is used for its abilities to enhance memory formation and also its neuroprotective properties. Centrophenoxine reduces lipofuscin which is the buildup of potassium that is the cause of brain cells becoming less efficient and dying. It is a choligenric compound which is lipid soluble and contains DMAE. Centrophenoxine also increases oxygen and glucose uptake in the brain and the increase of glucose uptake results in centrophenoxine helping to rectify the damage done to the brain that comes as a result of aging. It is said that the brain uses 20 percent of the oxygen available in the body and if the oxygen levels in the body become deficient then the brain does not operate as well as it could. So by increasing the flow of oxygen to the brain, centrophenoxine helps to increase the efficiency and productiveness of the brain in general.

lucid dreaming with nootropicsCentrophenoxine Benefits

However, centrophenoxine does not only help improve memory but also helps to protect memory and it is said to possibly reverse the effects that come as a result of aging of the brain. It also increases RNA which is used by neurons to create protein which is used to repair damaged cells in the brain. There have been studies done that show that centrophenoxine increases acetylcholinesterase activity in the brain stem in aged rats. What this essentially means is that the increase of acetylcholinesterase activity could be implicated in the reversal of neurodegradation. A double-blind study showed that centrophenoxine improved the cognitive performance of people who were suffering from age-related mental decline.

Centrophenoxine and Cognition

Overall, centrophenoxine improves cognitive functionality in the brain and also increases levels of serotonin, noradrenaline, and dopamine. Additionally, it is able to improve mood and can lead to a feeling of general well being. It also helps to support short-term memory due to the release of acetylcholine and some even think that it helps to promote the production of RNA. Also, it is thought that centrophenoxine helps to improve neuron fluidity and communication. This improvement links up with general thinking and cognition. Centrophenoxine powder is also thought to be a strong antioxidant and able to scavenge free radicals within the brain. There are also researchers who think centrophenoxine could help to alleviate cellular damage that comes as a result of different types of toxins.

Centrophenoxine Dosage

Cenotrphenoxine dosage is generally 250 to 3,000 milligrams daily. It is normally taken in doses that are equally divided throughout the day.

Centrophenoxine Side Effects

It is not recommended to take centrophenoxine at night or before you go to bed. It is smart to start out with a lower dose and increase gradually. Cycle off for a few days every 10 days to prevent excessive acetylcholine buildup. Centrophenoxine side effects could include muscle aches or pains which could also be the sign of overdose.

Sources:

  1. http://www.ncbi.nlm.nih.gov/pubmed/8367013
  2. http://www.ncbi.nlm.nih.gov/pubmed/6191765
  3. http://www.ncbi.nlm.nih.gov/pubmed/15374499

Choline Bitartrate Benefits and Dosage Reviewed

What is Choline Bitartrate?

Choline bitartrate is part of the b-complex vitamin family and can be found in foods such as meat, peanuts, and eggs. It can be naturally produced by the body and it is also water soluble. However, it is also an essential nutrient and therefore should be included as part of a balanced diet. Choline supplements provide many health benefits and play an important role in helping the brain and nervous system to function properly. Choline is also essential in muscle contraction and movement and plays an important role in coordination. Research shows that choline may be effective in helping to prevent diseases such as arteriosclerosis and memory-related diseases.Choline bitartrate benefits brain health.

Choline Bitartrate Benefits

It is also recommended that women consume adequate amounts of choline bitartrate because it may reduce the risk of colon cancer and breast cancer. Additionally, in pregnant women a deficiency in choline could lead to an increased risk of premature birth. Lack of choline could also negatively affect the development of the baby’s memory. Choline is excreted through urine, similar to B vitamins, which could lead to a deficiency in the body. Supplementation of additional foods that are rich in choline can correct this deficiency.

There are many benefits of choline bitartrate including nerve development, transportation of fat through the body, and growth of cell membranes. It is also believed that choline is important for the brain and muscles to function. Generally, choline has been found to be important in both the maintenance and development of protection against disease. Choline also has the ability to protect and heal the liver and keeps fatty deposits in the liver from accumulating. Choline also promotes equal distribution of fat in the body. It is also said that choline supplements can help to prevent liver disease.

Choline bitartrate benefits include increased focus, memory formation, and muscle contraction. Studies have shown that choline supplementation can prevent neurological decline associated with aging. It has also been linked to reducing the levels of homocysteine which is a risk factor for heart disease. Many people take choline with piracetam and find that the two complement each other well. Choline can also be taken alone although it generally is not. Overall, choline has many health benefits and is especially helpful in preventing age-related memory decline. It can also be used as a cognitive enhancer and helps to improve memory. If you are searching for a supplement that has cognitive boosting properties then you may want to look into choline. However, you may also want to look into piracetam and consider mixing the two as many reviewers have reported the combination to be very effective.

Choline Bitartrate Dosage

The recommended choline bitartrate dosage is around 425 milligrams for women and 550 milligrams for men daily. It is said that during pregnancy higher dosages of around 550 milligrams may be needed although a healthcare practitioner should be consulted first for more accurate recommendations.

Where to Buy Choline Bitartrate: Powder, Capsules, Tubs

If you’re looking for a hiqh quality, affordable choline source, Powdercity.com offers Choline Bitartrate in powder, capsule and tub form. The bulk powder comes in 100g, 500g and 1kg variants and the capsules come in 30, 60 or 180 count bottles. The tub contains 100g of Choline Bitartrate powder.

Choline Bitartrate Sources

  1. http://www.ncbi.nlm.nih.gov/pubmed/21900997
  2. http://www.ncbi.nlm.nih.gov/pubmed/21118604
  3. http://www.ncbi.nlm.nih.gov/pubmed/21475195

Aniracetam Review: Side Effects, Benefits, and Dosage

Aniracetam is a supplement that is used to stimulate AMPA (alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid) receptors in the brain. On a chemical level, aniracetam is a member of the racetam class of compounds. It is a type of nootropic that is mainly used to enhance brain function, sharpen memory, increase mental alertness, and improve concentration.

Aniracetam Benefits

There have been clinical trials that tested the health effects of aniracetam and concluded that it can offer a variety of certain health benefits. Aniracetam has been found to decrease the rate of receptor desensitization which would suggest that it is actually a potential benefit to memory formation. Aniracetam benefits users by increasing the release of serotonin and dopamine through the cholinergic mechanisms that are in the prefrontal cortex with implications in improving judgment. This could explain the nootropics ability to have a relaxing and calming effect on the mind and body.

Aniracetam is a stronger nootropic compared to piracetam, the granddaddy of the racetam family. The makeup of people who use aniracetam ranges widely, from the elderly who are looking to boost cognitive function to young people who are looking to enhance and increase their mental ability. Aniracetam works by stimulating the central nervous system and like piracetam is also used to increase communication between the right and left side of the brain. The effects of aniracetam are that it increases supply of oxygen to the brain cells, improves cognition and memory retention, increases blood circulation to the brain, and increases energy.

Aniracetam Side Effects

Aniracetam also provides these benefits with usually very little or no side effects. However, aniracetam side effects could include insomnia, headaches, nausea or rash. They are also generally very uncommon in most people.

Aniracetam Dosage

Most users take around 1 to 1.5 grams taken with food. However, daily dosages between 750 and 3,000 milligrams have also been considered safe although larger doses should be taken in smaller doses throughout the course of the day to prevent side effects such as headaches and nausea. You can buy aniracetam from supplement health stores as a bulk powder to save money (you can buy capsules separately to create your own capsules if you so desire). Overall aniracetam has been proven to be very effective for enhancing cognitive functions and helping to not only improve memory recall but reduce memory decline dramatically.

If you are looking for a solution that is more powerful than piracetam and will help to enhance your brain functionality then you should definitely check out aniracetam.

Aniracetam Reviews

Check out what people just like you have to say about their experience in these Aniracetam reviews.

Aniracetam and anxiety. I took this and felt completely relaxed at a group meeting. Usually I get social anxiety but this really helped, great stuff!R.B.

‘Very noticeable effects. Felt definite decrease in public speaking anxiety. I also had very good memory recall.’ -Bill

‘It works. Awesome product…it delivers as advertised!’ -Andrew R

‘Great! I generally take 1 gram in the morning and coffee or tea with 1 tablespoon of coconut oil. The effects are PROFOUND and I find cognitive activities as well as physical ones happen with ease. Personally for me it works wonders.’ -David C.

‘My son has really benefited from the Aniracetam, he did not care for the Oxiracetam because it made him feel “spaced out.” So, we went back to the Aniracetam.’ -Melba

‘Improves my mood a lot. I feel more comfortable being around a lot of people. I have social anxiety and it helps with that. It also helps with focus, motivation, and concentration. Not as much as noopept does but I can notice a difference. I have to take 500mg-1g at a time twice a day. Anymore than that and I get brain fog. The only bad thing about aniracetam is that it lasts 3-4 hours and its half life is 1-2 hours and I have to take a choline with it between 300-500mg or I will get a headache that lasts all day.’ -Al

‘I decided to try Aniracetam instead of other racetams because I have to go to work in the evenings after I workout. Before I took Aniracetam, I would be either brain dead from my workout or jittery from caffeine after taking a pre-workout a few hours before hand. Aniracetam helps keep my mind clear and alert, and I don’t get jittery or wired if I have caffeine.’ -Chris

‘Great for depression and anxiety, 750mg to start with 500mg Choline and a glass of milk or other fat such as unrefined coconut oil since this is fat soluble. Aniracetam really helped with my feelings of worry and anxiety, organizing my thought patterns, speech, recognition, memory, and decisiveness.’ -Damian

Sources:

  1. http://www.ncbi.nlm.nih.gov/pubmed/6817363
  2. http://www.ncbi.nlm.nih.gov/pubmed/10627576
  3. http://www.ncbi.nlm.nih.gov/pubmed/8199398

The Inner Workings of Racetams

Racetams are a family of supplements known as nootropics. This comes from the Greek meaning ‘mind-turning,’ due to their ability to affect brain and cognitive functions. There are a number of supplements classified within this racetam family and the inner workings of each, including their mechanisms of action are all fairly similar. Yet, at the same time, each of these supplements can offer slightly different benefits and results. How does each of the major racetams work? Can they be taken together, or in different combinations?

Piracetam Review

The first nootropic was Piracetam, first synthesized in 1964 by a Belgian pharmaceutical company. It does appear to have some interesting effects and benefits upon improving cognitive functions, especially in those suffering from age-related mental decline. There is also no toxicity to this supplement.

Despite the fact that this has been on the market for a number of years, the mechanisms of action are still not entirely understood. It appears to enhance membrane fluidity by interacting directly with cell membranes. It controls excessive excitation within the brain largely by binding to both glutamate receptors and affecting the levels of circulating acetylcholine.

Aniracetam Review

Another entry into the racetam family, Aniracetam, is more potent than Piracetam. It also is one of the few fat-soluble racetam members and this may be why many consider it to be more effective. This one is more geared towards improving creativity and holistic thinking, rather than Piracetam which seems to exert mild effects in a more general fashion. Aniracetam also has shown a surprising efficacy in helping to reduce feelings of anxiety and low moods.

The mechanism of action in this supplement is believed to be a positive modulation of certain excitatory receptors in the brain known as AMPA receptors. It also decreases the rate of receptor desensitization. This may be why the effects typical manifest as controlled and prolonged neurological stimulation.

Oxiracetam Review

The main benefit of Oxiracetam is potency. It is actually quite similar to the original Piracetam, improving many of the same processes. These beneficial processes include improving the effectiveness of brain training games, boosting memory, improving general cognitive function, repairing damage done by excessive alcohol consumption, and possibly effective in dealing with cognitive disorders and age-related memory loss.

Oxiracetam is fast acting and believed to effect the production of both acetylcholine and glutamate. These neurotransmitters play an important role in our ability to sustain attention in the CNS. This is also likely why short-term memory and learning are positively affected.

Bottom Line

While all the members of the racetam family do have essentially similar mechanisms of action, we should still keep in mind a number of other factors. First, each supplement will affect different people in different ways. Also, the potency can vary considerably from supplement to supplement. Also bear in mind that stacking different nootropics and ractems may provide a synergistic effect, this should be done carefully and under controlled circumstances.

The Top 3 Mood Boosting Nootropics

Many people are looking for safe and natural methods to help boost or improve their mood. Whether this means combating mood disorders or to improve concentration and help with a loss of memory, there are a number of supplements which can help. It has been estimated that nearly 10% of all Americans have some form of depression. This probably does not even include those with mild memory problems or those suffering from temporary mood issues. Some of the top nootropic supplements, a few of which are also considered to be cognitive enhancers, may be just what the doctor ordered.

Aniracetam

This is a well-documented memory supplement that is a favorite mood booster for many. One of its specific effects seems to be increasing energy levels, which helps to improve motivation. Users are better able to actually get started on projects and accomplish needed tasks. There are also more subtle (although still quite noticeable) effects on feelings of well-being. It should also be noted that not everyone will have these exact same reactions, so feel free to try one of the others on the list.

Sulbutiamine

Many times, a poor mood is the result of chemical imbalances within the brain or simply an ineffective method of transmitting some of the brain hormones. A good example of this would be dopamine, which scientists believe responsible for mood and movement. Sulbutiamine actually seems to have the effect of increasing the amount of dopamine circulating within the brain. Many people who have shyness often also have low dopamine levels. Interestingly enough, there does not appear to be any kind of amphetamine-like stimulation as a side effect. You can buy sulbutiamine here.

Noopept

This is another nootropic that is actually a bit similar to Aniracetam. Researchers think that they both effect dopamine and serotonin receptor sites in a similar fashion. Noopept is actually a bit stronger than Aniracetam, so it is certainly possible that one might be more to your liking than another. This supplement does appear to increase feelings of well-being and enhancing motivation. There have also been reports of some anxiolytic effects, although this does not occur in all users.

Nootropics have been studied fairly extensively, especially in recent years. There is also a lot of anecdotal evidence and user reports to indicate that they do have a positive mood-boosting effect. If this is something that sounds interesting, be sure to try one or all of these different mood-booster supplements.