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Centrophenoxine Review

Centrophenoxine is an ester of pCPA and DMAE and is used for its abilities to enhance memory formation and also its neuroprotective properties. Centrophenoxine reduces lipofuscin which is the buildup of potassium that is the cause of brain cells becoming less efficient and dying. It is a choligenric compound which is lipid soluble and contains DMAE. Centrophenoxine also increases oxygen and glucose uptake in the brain and the increase of glucose uptake results in centrophenoxine helping to rectify the damage done to the brain that comes as a result of aging. It is said that the brain uses 20 percent of the oxygen available in the body and if the oxygen levels in the body become deficient then the brain does not operate as well as it could. So by increasing the flow of oxygen to the brain, centrophenoxine helps to increase the efficiency and productiveness of the brain in general.

lucid dreaming with nootropicsCentrophenoxine Benefits

However, centrophenoxine does not only help improve memory but also helps to protect memory and it is said to possibly reverse the effects that come as a result of aging of the brain. It also increases RNA which is used by neurons to create protein which is used to repair damaged cells in the brain. There have been studies done that show that centrophenoxine increases acetylcholinesterase activity in the brain stem in aged rats. What this essentially means is that the increase of acetylcholinesterase activity could be implicated in the reversal of neurodegradation. A double-blind study showed that centrophenoxine improved the cognitive performance of people who were suffering from age-related mental decline.

Centrophenoxine and Cognition

Overall, centrophenoxine improves cognitive functionality in the brain and also increases levels of serotonin, noradrenaline, and dopamine. Additionally, it is able to improve mood and can lead to a feeling of general well being. It also helps to support short-term memory due to the release of acetylcholine and some even think that it helps to promote the production of RNA. Also, it is thought that centrophenoxine helps to improve neuron fluidity and communication. This improvement links up with general thinking and cognition. Centrophenoxine powder is also thought to be a strong antioxidant and able to scavenge free radicals within the brain. There are also researchers who think centrophenoxine could help to alleviate cellular damage that comes as a result of different types of toxins.

Centrophenoxine Dosage

Cenotrphenoxine dosage is generally 250 to 3,000 milligrams daily. It is normally taken in doses that are equally divided throughout the day.

Centrophenoxine Side Effects

It is not recommended to take centrophenoxine at night or before you go to bed. It is smart to start out with a lower dose and increase gradually. Cycle off for a few days every 10 days to prevent excessive acetylcholine buildup. Centrophenoxine side effects could include muscle aches or pains which could also be the sign of overdose.

Sources:

  1. http://www.ncbi.nlm.nih.gov/pubmed/8367013
  2. http://www.ncbi.nlm.nih.gov/pubmed/6191765
  3. http://www.ncbi.nlm.nih.gov/pubmed/15374499

Aniracetam Review: Side Effects, Benefits, and Dosage

Aniracetam is a supplement that is used to stimulate AMPA (alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid) receptors in the brain. On a chemical level, aniracetam is a member of the racetam class of compounds. It is a type of nootropic that is mainly used to enhance brain function, sharpen memory, increase mental alertness, and improve concentration.

Aniracetam Benefits

There have been clinical trials that tested the health effects of aniracetam and concluded that it can offer a variety of certain health benefits. Aniracetam has been found to decrease the rate of receptor desensitization which would suggest that it is actually a potential benefit to memory formation. Aniracetam benefits users by increasing the release of serotonin and dopamine through the cholinergic mechanisms that are in the prefrontal cortex with implications in improving judgment. This could explain the nootropics ability to have a relaxing and calming effect on the mind and body.

See our main aniracetam article on a more extensive list of benefits and some interesting studies.

Aniracetam is a stronger nootropic compared to piracetam, the granddaddy of the racetam family. The makeup of people who use aniracetam ranges widely, from the elderly who are looking to boost cognitive function to young people who are looking to enhance and increase their mental ability. Aniracetam works by stimulating the central nervous system and like piracetam is also used to increase communication between the right and left side of the brain. The effects of aniracetam are that it increases supply of oxygen to the brain cells, improves cognition and memory retention, increases blood circulation to the brain, and increases energy.

Aniracetam Side Effects

Aniracetam also provides these benefits with usually very little or no side effects. However, aniracetam side effects could include insomnia, headaches, nausea or rash. They are also generally very uncommon in most people.

Aniracetam Dosage

Most users take around 1 to 1.5 grams taken with food. However, daily dosages between 750 and 3,000 milligrams have also been considered safe although larger doses should be taken in smaller doses throughout the course of the day to prevent side effects such as headaches and nausea. You can buy aniracetam from supplement health stores as a bulk powder to save money (you can buy capsules separately to create your own capsules if you so desire). Overall aniracetam has been proven to be very effective for enhancing cognitive functions and helping to not only improve memory recall but reduce memory decline dramatically.

If you are looking for a solution that is more powerful than piracetam and will help to enhance your brain functionality then you should definitely check out aniracetam.

Aniracetam Reviews

Check out what people just like you have to say about their experience in these Aniracetam reviews.

Aniracetam and anxiety. I took this and felt completely relaxed at a group meeting. Usually I get social anxiety but this really helped, great stuff!R.B.

‘Very noticeable effects. Felt definite decrease in public speaking anxiety. I also had very good memory recall.’ -Bill

‘It works. Awesome product…it delivers as advertised!’ -Andrew R

‘Great! I generally take 1 gram in the morning and coffee or tea with 1 tablespoon of coconut oil. The effects are PROFOUND and I find cognitive activities as well as physical ones happen with ease. Personally for me it works wonders.’ -David C.

‘My son has really benefited from the Aniracetam, he did not care for the Oxiracetam because it made him feel “spaced out.” So, we went back to the Aniracetam.’ -Melba

‘Improves my mood a lot. I feel more comfortable being around a lot of people. I have social anxiety and it helps with that. It also helps with focus, motivation, and concentration. Not as much as noopept does but I can notice a difference. I have to take 500mg-1g at a time twice a day. Anymore than that and I get brain fog. The only bad thing about aniracetam is that it lasts 3-4 hours and its half life is 1-2 hours and I have to take a choline with it between 300-500mg or I will get a headache that lasts all day.’ -Al

‘I decided to try Aniracetam instead of other racetams because I have to go to work in the evenings after I workout. Before I took Aniracetam, I would be either brain dead from my workout or jittery from caffeine after taking a pre-workout a few hours before hand. Aniracetam helps keep my mind clear and alert, and I don’t get jittery or wired if I have caffeine.’ -Chris

‘Great for depression and anxiety, 750mg to start with 500mg Choline and a glass of milk or other fat such as unrefined coconut oil since this is fat soluble. Aniracetam really helped with my feelings of worry and anxiety, organizing my thought patterns, speech, recognition, memory, and decisiveness.’ -Damian

Sources:

  1. http://www.ncbi.nlm.nih.gov/pubmed/6817363
  2. http://www.ncbi.nlm.nih.gov/pubmed/10627576
  3. http://www.ncbi.nlm.nih.gov/pubmed/8199398